Breast Embryology Multiple-Choice Questions
Question: 1. Following are true for lymphatic drainage of the breast except:
- Apical nodes are also called infraclavicular nodes
- Apical nodes drain into subclavian lymph trunk
- Posterior third of the breast drain into supraclavicular nodes
- For detection of sentinel node, ideal site is subdermal plexus around nipple
Answer: 3. Posterior third of the breast drain into supraclavicular nodes
Question: 2. Following are true for advantages of MRI in the breast except:
- It is the best modality for women with breast implants
- Screening in women with strong family history
- It is also better than ultrasound to image axilla
- It can distinguish scar from recurrence in women who have undergone breast conservative surgery
Answer: 3. It is also better than ultrasound to image axilla
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Question: 3. Following are true for retraction of the nipple except:
- Slit-like retraction is seen in duct ectasia
- Circumferential retraction is seen in carcinoma breast
- Extension of the growth along the lactiferous duct causes retraction of the nipple
- Horizontal retraction can occur at puberty suggests fibroadenomas
Answer: 4. Horizontal retraction can occur at puberty suggests fibroadenomas
Question: 4. Following are true lactational mastitis except:
- Retracted nipple is one of the causes
- Majority of the cases are due to anaerobic infection
- Repeated aspiration is recommended treatment
- Fluctuation is a late sign
Answer: 2. Majority of the cases are due to anaerobic infection
Question: 5. Smoking is associated with which of the following breast diseases?
- Tuberculosis
- Breast abscess
- Duct ectasia
- Mondor’s disease
Answer: 3. Duct ectasia
Question: 6. Following is not the common sign of periductal mastitis:
- Discharge per nipple
- Indurated mass
- Fistula
- Circumferential retraction of the nipple
Answer: 4. Circumferential retraction of the nipple
Question: 7. The widely used first investigation of choice in a lady of 25 years with lump breast is:
- Ultrasonography
- CT scan
- MRI
- FNAC
Answer: 1. Ultrasonography
Question: 8. Which one of the following is not the treatment for mastalgia?
- Evening primrose oil
- Danazol
- Steroids
- Bromocriptine
Answer: 3. Steroids
Question: 9. Following are true for parathyroid hyperplasia except:
- Usual age of presentation is 20 years
- Large tumour with bosselated surface
- It may have high mitotic index
- Rarely develop into sarcoma
Answer: 1. Usual age of presentation is 20 years
Question: 10. Which one of the following is the treatment of choice for early breast cancer in a 30-year-old lady who is 4 months pregnant?
- Chemotherapy
- Tamoxifen
- Local wide excision
- Modified radical mastectomy
Answer: 4. Modified radical mastectomy
Question: 11. Which is the drug used in a patient to prevent breast cancer with positive family history but unlikely carrier of breast cancer gene?
- Adriamycin
- Tamoxifen
- Letrozole
- Trastuzumab
Answer: 4. Tamoxifen
Question: 12. Which one of the operative steps is not done in modified radical mastectomy?
- Total mastectomy
- Axillary block dissection
- Removal of pectoralis major
- Removal of pectoralis minor
Answer: 3. Removal of pectoralis major
Question: 13. Following are the components of breast conservative surgery except:
- Excision of tumour plus a rim of 1 cm of normal breast tissue
- Axillary block dissection
- Routine removal of the skin over the tumour
- Sentinel node biopsy in selected patients
Answer: 3. Routine removal of the skin over the tumour
Question: 14. Following are true for radiotherapy in carcinoma
breast except:
- It should be given after breast conservative surgery
- Large tumours after surgery require radiotherapy
- Extensive lymphovascular invasion is an indication
- Routinely given to axilla after a complete block dissection
Answer: 4. Routinely given to axilla after a complete block dissection
Question: 15. Following are true for aromatase inhibitors except:
- Maximum use in the premenopausal patients
- Relapse free survival is prolonged
- Reduction in the contralateral disease
- Increase in the bone density loss
Answer: 1. Maximum use in the premenopausal patients
Question: 16. Which of the following is the most important aetiological factor for carcinoma breast?
- Oral Contraceptive Pills
- Childhood Irradiation For Hodgkin’S Lymphoma
- Duct Ectasia
- Racial Factors
Answer: 2. Childhood irradiation for Hodgkin’s lymphoma
Question: 17. Following are true for ductal carcinoma in situ (DCIS) except:
- It is usually unilateral
- Multifocal
- Excision with or without radiotherapy is the treatment of choice
- No role for chemotherapy
Answer: 2. Multifocal
Question: 18. Following are true for inflammatory carcinoma except:
- It results in blockage of dermal lymphatics
- It is considered as locally advanced breast cancer
- Neoadjuvant chemotherapy is the treatment ofchoice
- Severe degree of inflammation present pathologically
Answer: 4. Severe degree of inflammation present pathologically
Question: 19. Following are true for lobular carcinoma in situ except:
- It is usually unilateral
- Multifocal
- Excision with or without radiotherapy is the treatment of choice
- 20% will develop into invasive carcinoma
Answer: 1. It is usually unilateral
Question: 20.Following are true about internal mammary lymph nodes except:
- They drain posterior part of the breast
- They communicate with subdiaphragmatic lymph nodes
- They are included in the staging system now
- Their involvement indicates metastatic disease
Answer: 4. Their involvement indicates metastatic disease
Question: 21. Following are true for sentinel node biopsy in carcinoma breast except:
- Injection Of Patent Blue Localises The Sentinel Node
- Injecting Into Subdermal Plexus Around The Nippleis Ideal
- Hand Held Gamma Camera Detects This
- It Is Ideal In Clinically Node Positive Axilla
Answer: 4. It Is Ideal In Clinically Node Positive Axilla
Question: 22. Following is an indication for radiotherapy to chest wall in carcinoma breast except:
- Extensive Lymphovascular Invasion
- Large Number Of Positive Nodes In The Axilla
- Base Is Involved By The Tumour
- Skin Is Infiltrated
Answer: 4. Skin Is Infiltrated
Question: 23. Following are true for tamoxifen except:
- It Is Widely Used As Hormonal Treatment In Premenopausal Patients
- It Decreases The Annual Recurrence By 25%
- It Also Has Benefit In Preventing Contralateral Breast Cancer
- It Is Not Recommended In Patients Who Have Family History Of Carcinoma Breast But Unlikely Carriers Of Breast Cancer Gene
Answer: 4. It Is Not Recommended In Patients Who Have Family History Of Carcinoma Breast But Unlikely Carriers Of Breast Cancer Gene
Question: 24. Treatment option for carcinoma breast in pregnancy is:
- Local wide excision
- Radiotherapy
- Chemotherapy
- Mastectomy
Answer: 4. Mastectomy
Question: 25. Which one of the following is not true in male breast cancer?
- Most Commonly It Is Infiltrating Duct Carcinoma
- Mostly It Presents As Bleeding Per Nipple
- Mostly Mastectomy Is Required
- Gynaecomastia Is A Predisposing Factor
Answer: 2. Mostly It Presents As Bleeding Per Nipple
Question: 26. When do you use vancomycin in breast abscess due to MRSA?
- All Cases
- Breast Abscess In Pregnant Patients
- Stage Of Mastitis To Prevent Progression To Abscess
- Breast Abscess With Systemic Toxicity
Answer: 4. Breast Abscess With Systemic Toxicity
Question: 27. Following are true for ductal carcinoma in situ except:
- Wide Excision And Radiotherapy Is Given
- Pre-Menopausal Women Are Treated With Tamoxifen Postoperatively
- Comedocarcinoma In Situ Requires Chemotherapy
- It Can Present As Mammographically Detected Microcalcification
Answer: 3. Comedocarcinoma In Situ Requires Chemotherapy
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