General Medicine

Gene Therapy Gene therapy Definition: Gene therapy is the insertion of genes into an individual’s cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. To be effective, the gene therapy requires methods that ensure the safe, efficient and stable introduction of genes into human … [Read more...] about Gene Therapy Pros And Cons

Structural Chromosomal Aberrations Q. Discuss chromosomal translocations with examples. (Or) What is reciprocal translocation? (Or) Write a note on Robertsonian translocation. Answer: Structural chromosomal aberrations may occur either during mitosis or meiosis. Types of chromosomal abnormality. Numerical abnormalities Aneuploidy Monosomy Trisomy … [Read more...] about Robertsonian Translocation

 Human Genome Project Human Genome Project Introduction Genome: A genome is the entire DNA in an organism, including its genes. The human genome is estimated to contain 30,000–40,000 genes that are divided among the 23 chromosomes. The 23 different chromosomes, 22 are autosomes (numbered 1–22) and 1 pair of sex chromosomes (X and Y). The functions of over 50% of … [Read more...] about  Human Genome Project

Kary Mullis discovered polymerase chain reaction in 1983. PCR is a method employed to amplify minute amount of DNA within a few hours. This technique consists of selective amplification of specific target nucleic acid sequences from total DNA by using primers specific for the target region to be amplified. Polymerase Chain Reaction And Its Applications Basic Steps … [Read more...] about Polymerase Chain Reaction ( PCR technology)

List the causes of papilledema Papilledema is the edema (swelling) of the optic disk >3 diopters. This term has been used only for passive swelling of the optic disk secondary to raised ICP. Causes of papilledema It develops due to obstruction of venous output along with stasis of axoplasmic flow within the optic nerve. It also develops due to any cause that … [Read more...] about Papilledema Causes