Lymphoma And The Lymphatic System Multiple Choice Question And Answers
Question 1. Which of the following is false regarding functions of the lymphatic system?
- Lymph circulation occurs through lymphatic venous junctions
- Lymphatic fluid contains macromolecules
- The right lymphatic duct drains into the internal jugular vein
- The lymphatic fluid from the intestines passes through the liver
Answer: 4. The lymphatic fluid from the intestines passes through the liver
Question 2. The following is true for lymph trunks except:
- They are lined by a single layer of endothelial cells
- Pulsations of the vessels help in lymph circulation
- The thoracic duct drains into the right internal jugular vein
- They do not accompany neurovascular bundles in the central nervous system
Answer: 3. The thoracic duct drains into the right internal jugular vein
Question 3. The following are risk factors for lower limb lymphoedema:
- Inguinal block dissection
- Pelvic radiotherapy
- Obesity
- Alcohol abuse
Answer: 4. Alcohol abuse
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Question 4. Stemmer’s sign refers to:
- Gross thickening of the subcutaneous tissue in a lymphoedematous leg
- The deep muscle of the leg is not involved
- Skin on the dorsum of the toes cannot be pinched
- Buffalo hump on the dorsum of the foot
Answer: 3. Skin on the dorsum of the toes cannot be pinched
Question 5. The following is true for filarial elephantiasis of the leg:
- It is caused by Wuchereria bancrofti
- It is transmitted by Culex fatigans
- Microfilariae do not produce any lesions
- Significant changes occur deep in the deep fascia
Answer: 4. Significant changes occur deep in the deep fascia
Question 6. The majority of primary lymphoedema is due to:
- Congenital hyperplasia of lymphatics
- Distal obliteration of lymphatics
- Proximal obliteration of lymphatics
- Central obliteration of lymphatics
Answer: 2. Distal obliteration of lymphatics
Question 7. Oxerutins used in lymphoedema act by the following mechanisms:
- Decrease capillary permeability
- Improve microcirculatory perfusion
- Stimulate interstitial macrophage proteolysis
- Increase platelet aggregation
Answer: 4. Increase platelet aggregation
Question 8. Which of the following is true regarding lymphoedema?
- Dermal lymphatics are never involved in filariasis
- Oxerutins are not used in lymphoedema
- Lymphoedema pressure bandage requires 0 mmHg pressure in the leg
- Lymphoedema does not predispose to malignancies
Answer: 1. Dermal lymphatics are never involved in filariasis
Question 9. Contiguous and centripetal spread occurs in:
- Hodgkin’s lymphoma
- Non-Hodgkin’s lymphoma
- Burkitt’s lymphoma
- Sézary’s syndrome
Answer: 1. Hodgkin’s lymphoma
Question 10. The following is true for lymphocytic predominance nodular lymphoma except:
- It has large atypical cells
- It expresses CD20+
- It is indolent
- It has a favourable prognosis
Answer: 1. It has large atypical cells
Question 11. The following are true about classical Hodgkin’s lymphoma except:
- Spread is contiguous
- Large atypical cells are seen
- B symptoms are characteristic
- CD15 and CD30 are expressed
Answer: 3. B symptoms are characteristic
Question 12. The following are the features of a Reed-Sternberg cell except:
- It is a giant cell
- It contains mirror-image nuclei
- It is a large multinucleated cell
- It is not derived from B lymphocytes
Answer: 4. It is not derived from B lymphocytes
Question 13. The following is true for mediastinal lymphoma except:
- It is the most common malignancy in the mediastinum
- Its response to chemotherapy is dramatic
- It is Hodgkin’s lymphoma
- The posterior compartment is commonly involved
Answer: 4. The posterior compartment is commonly involved
Question 14. The following are no longer followed in lymphomas:
- Pelvic radiotherapy
- Splenectomy as a staging procedure
- Rye’s classification
- ABVD regimen is commonly given
Answer: 4. ABVD regimen is commonly given
Question 15. The following are the causes of epitrochlear node enlargement:
- Hodgkin’s lymphoma
- Non-Hodgkin’s lymphoma
- Secondary syphilis
- Cat-scratch fever
Answer: 1. Hodgkin’s lymphoma
Question 16. The following is true for Rituximab except:
- It is a monoclonal antibody against the protein CD20
- It is used to treat leukaemia
- It can also be used to treat follicular lymphomas
- It has no role in transplant rejections
Answer: 4. It has no role in transplant rejections
Question 17. The following is true for Burkitt’s lymphoma except:
- It is associated with Epstein-Barr virus
- It is not associated with heavy malarial infestation
- It affects the jaw and orbital bones
- It gives a starry sky appearance on histopathology
Answer: 2. It is not associated with heavy malarial infestation
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